Bioinformatics: Publication in Science
www.hhu.de
Bioinformaticians from Heinrich Heine University Düsseldorf (HHU) and the university in Linköping (Sweden) have established that the genes in bacterial genomes are arranged in a meaningful order. In the renowned scientific journal Science, they describe that the genes are arranged by function: If they become increasingly important at faster growth, they are located near the origin of DNA replication. Accordingly, their position influences how their activity changes with the growth rate.
      • lemming@sh.itjust.works
        1·
        5 days ago

        It’s not so much about nuclear envelope and more about ends. DNA polymerase (an enzyme that builds new DNA) cannot copy the whole end - there are a few bases that should be at the end but cannot be added. Eukaryota deal with it by a complex mechanism (they have telomeres), but it allows for multiple chromosomes and therefore larger genomes. Bacteria have a circular genome instead, a circle doesn’t have an end, so they can copy as much as they need.

        BTW, mitochondria and plastids, being former bacteria, also have circular genomes.